Facile synthesis of 3-substituted thieno[3,2-b]furan derivatives

被引:9
作者
Hergue, Noemie [1 ]
Mallet, Charlotte [1 ]
Touvron, Julia [1 ]
Allain, Magali [1 ]
Leriche, Philippe [1 ]
Frere, Pierre [1 ]
机构
[1] Univ Angers, CNRS, Lab Chim & Ingn Mol Angers, CIMA UMR 6200,Grp SCL, F-49045 Angers, France
关键词
furan; thienofuran; Dieckmann cyclization; heterocyclic chemistry;
D O I
10.1016/j.tetlet.2008.02.058
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A facile synthesis of dimethyl 3-hydroxythieno[3,2-b]furan-2,5-dicarboxylate is reported from the available methyl thioglycolate and dimethyl acetylenedicarboxylate starting materials. This compound represents an efficient precursor for the synthesis of 3-substituted thieno[3,2-b]furan derivatives. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:2425 / 2428
页数:4
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