Asymmetric hydroarylation of norbornene derivatives catalyzed by palladium complexes of chiral quinolinyl-oxazolines

被引：37

作者：

Wu, XY

Xu, HD

Tang, FY

Zhou, QL ^{[1
]}

机构：

[1] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

[2] Nankai Univ, State Key Lab, Tianjin 300071, Peoples R China

[3] Nankai Univ, Inst Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 18期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0957-4166(01)00436-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Chiral quinolinyl-oxazolines were found to be efficient ligands in the enantioselective palladium-catalyzed Heck-type hydroarylation of norbornene and its derivatives. The ligands with a medium sized alkyl group on the oxazoline ring provided higher enantioselectivities. The presence of elect ron-don ati ng substituents on the aryl iodide increased the selectivity and the yield of the reactions. The configuration of (-)-exo-2-phenylbicyclo[2.2.1]heptane has been assigned as (1R, 2'R). (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2565 / 2569

页数：5

共 27 条

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