The cell biology of tetrapyrroles: a life and death struggle

被引：251

作者：

Mochizuki, Nobuyoshi ^{[2
]}

Tanaka, Ryouichi ^{[3
]}

Grimm, Bernhard ^{[4
]}

Masuda, Tatsuru ^{[5
]}

Moulin, Michael ^{[6
]}

Smith, Alison G. ^{[6
]}

Tanaka, Ayumi ^{[3
]}

Terry, Matthew J. ^{[1
]}

机构：

[1] Univ Southampton, Sch Biol Sci, Southampton SO16 7PX, Hants, England

[2] Kyoto Univ, Grad Sch Sci, Dept Bot, Kyoto 6068502, Japan

[3] Hokkaido Univ, Inst Low Temp Sci, Sapporo, Hokkaido 0600819, Japan

[4] Humboldt Univ, Inst Biol Plant Physiol, D-10115 Berlin, Germany

[5] Univ Tokyo, Grad Sch Arts & Sci, Tokyo 1538902, Japan

[6] Univ Cambridge, Dept Plant Sci, Cambridge CB2 3EA, England

来源：

TRENDS IN PLANT SCIENCE | 2010年 / 15卷 / 09期

基金：

英国生物技术与生命科学研究理事会;

关键词：

MG-PROTOPORPHYRIN-IX; EXCITATION-ENERGY TRANSFER; NUCLEAR GENE-EXPRESSION; REV-ERB-ALPHA; MAGNESIUM-CHELATASE; ARABIDOPSIS-THALIANA; CHLOROPLAST BIOGENESIS; CHLOROPHYLL SYNTHESIS; HEME-BIOSYNTHESIS; FERROCHELATASE ACTIVITY;

D O I：

10.1016/j.tplants.2010.05.012

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Tetrapyrroles such as chlorophyll and heme are co-factors for essential proteins involved in a wide variety of crucial cellular functions. Nearly 2% of the proteins encoded by the Arabidopsis thaliana genome are thought to bind tetrapyrroles, demonstrating their central role in plant metabolism. Although the enzymes required for tetrapyrrole biosynthesis are well characterized, there are still major questions about the regulation of the pathway, and the transport of tetrapyrroles within cells. These issues are important, as misregulation of tetrapyrrole metabolism can lead to severe photo-oxidative stress, and because tetrapyrroles have been implicated in signaling pathways coordinating interactions between plant organelles. In this review, we discuss the cell biology of tetrapyrrole metabolism and its implications for tetrapyrroles as signaling molecules.

引用

页码：488 / 498

页数：11

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