Next-generation genomics of Pseudomonas syringae

被引:30
作者
O'Brien, Heath E. [1 ]
Desveaux, Darrell [1 ,2 ]
Guttman, David S. [1 ,2 ]
机构
[1] Univ Toronto, Dept Cell & Syst Biol, Toronto, ON M5S 3B2, Canada
[2] Univ Toronto, Ctr Anal Genome Evolut & Funct, Toronto, ON M5S 3B2, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
SEQUENCE; VIRULENCE; PATHOGEN; EVOLUTION; EFFECTOR; REVEALS; GENES; ARABIDOPSIS; ALGINATE; ACCURATE;
D O I
10.1016/j.mib.2010.12.007
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The first wave of Pseudomonas syringae next-generation genomic studies has revealed insights into host-specific virulence and immunity, genome dynamics and evolution, and genetic and metabolic specialization. These studies have further enhanced our understanding of type III effector diversity, identified an atypical type III secretion system (T3SS) in a new clade of nonpathogenic P. syringae, identified metabolic pathways common to pathogens of woody hosts and revealed extensive genomic diversity among strains that infect common hosts. In general, these discoveries have illustrated the utility of draft genome sequencing for quickly and economically identifying candidate loci for more refined genetic and functional analyses.
引用
收藏
页码:24 / 30
页数:7
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