Restricted-carbohydrate diets in patients with type 2 diabetes: A meta-analysis

被引：138

作者：

Kirk, Julienne K. ^{[1
]}

Graves, Darby E. ^{[1
]}

Craven, Timothy E. ^{[2
]}

Lipkin, Edward W. ^{[3
]}

Austin, Mary ^{[4
]}

Margolis, Karen L. ^{[5
]}

机构：

[1] Wake Forest Univ, Sch Med, Dept Family & Community Med, Winston Salem, NC 27157 USA

[2] Wake Forest Univ, Sch Med, Dept Publ Hlth Sci, Winston Salem, NC 27157 USA

[3] Univ Washington, Seattle, WA 98195 USA

[4] Austin Grp LLC, Shelby Township, MI USA

[5] HealthPartners Res Fdn, Minneapolis, MN USA

来源：

JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION | 2008年 / 108卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/j.jada.2007.10.003

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Many current popular weight-loss diets advocate restricting carbohydrates, but risks and benefits of these diets for patients with diabetes is unclear. We searched for articles published in English between 1980 and April 2006 regarding carbohydrate-restricted diets that included and reported separate results for adult, nonpregnant patients with type 2 diabetes. Articles were limited to studies completed in the United States and Canada. Available data on study design; carbohydrate composition of diet; duration of diet; and the outcomes of weight, lipid levels (total, low-density lipoprotein and high-density lipoprotein cholesterol, and triglycerides), hemoglobin Ale percent and/or fasting glucose were extracted. A total of 56 studies or reviews were evaluated. Thirteen studies met our inclusion criteria. Meta-regression analyses show that hemoglobin Ale, fasting glucose, and some lipid fractions (triglycerides) improved with lower carbohydrate-content diets. Overall effect on weight was equivocal among the studies evaluated in this meta-analysis. Randomized, controlled studies of restricted-carbohydrate diets in patients with diabetes need to be conducted in order to evaluate the overall sustainability of outcomes and long-term safety.

引用

页码：91 / 100

页数：10

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