Are desmosomes more than tethers for intermediate filaments?

被引：305

作者：

Green, KJ ^{[1
]}

Gaudry, CA

机构：

[1] Northwestern Univ, Sch Med, Dept Pathol, Chicago, IL 60611 USA

[2] Northwestern Univ, Sch Med, Dept Dermatol, Chicago, IL 60611 USA

[3] Northwestern Univ, Sch Med, Robert H Lurie Canc Ctr, Chicago, IL 60611 USA

来源：

NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2000年 / 1卷 / 03期

关键词：

D O I：

10.1038/35043032

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Desmosomes are intercellular adhesive junctions that anchor intermediate filaments at membrane-associated plaques in adjoining cells, thereby forming a three-dimensional supracellular scaffolding that provides tissues with mechanical strength. But desmosomes have also recently been recognized as sensors that respond to environmental and cellular cues by modulating their assembly state and, possibly, their signalling functions.

引用

页码：208 / 216

页数：9

共 112 条

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