Latonduines A and B, new alkaloids isolated from the marine sponge Stylissa carteri:: Structure elucidation, synthesis, and biogenetic implications

被引：60

作者：

Linington, RG

Williams, DE

Tahir, A

van Soest, R

Andersen, RJ ^{[1
]}

机构：

[1] Univ British Columbia, Dept Chem, Vancouver, BC V6T 1Z1, Canada

[2] Univ British Columbia, Dept Earth & Ocean Sci, Vancouver, BC V6T 1Z1, Canada

[3] Univ Hasanuddin, Fac Fisheries & Marine Sci, Ujung Pandang, Indonesia

[4] Univ Amsterdam, Museum Zool, Amsterdam, Netherlands

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 15期

关键词：

D O I：

10.1021/ol034950b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Latonduines A (6) and B (7), two new alkaloids with unprecedented heterocyclic skeletons, have been isolated from the Indonesian marine sponge Stylissa carted. The structures of the, latonduines were elucidated by analysis of spectroscopic data and confirmed by the total synthesis of latonduine A (6). It is proposed that ornithine is the biogenetic precursor to the aminopyrimidine fragment of the latonduines.

引用

页码：2735 / 2738

页数：4

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