Copper-mediated synthesis of N-acyl vinylogous carbamic acids and derivatives:: Synthesis of the antibiotic CJ-15,801

被引:138
作者
Han, C
Shen, RC
Su, S
Porco, JA
机构
[1] Boston Univ, Dept Chem, Boston, MA 02215 USA
[2] Boston Univ, Ctr Chem Methodol & Lib Dev, Boston, MA 02215 USA
关键词
D O I
10.1021/ol0360041
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Copper(I)-mediated C-N bond formation has been employed to prepare both N-acyl vinylogous carbamic acids and ureas. The novel N-acyl vinylogous carbamic acid antibiotic, CJ-15,801, was synthesized using this methodology.
引用
收藏
页码:27 / 30
页数:4
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共 44 条
  • [41] A mild and efficient method for chemoselective deprotection of acetonides by bismuth(III) trichloride
    Swamy, NR
    Venkateswarlu, Y
    [J]. TETRAHEDRON LETTERS, 2002, 43 (42) : 7549 - 7552
  • [42] FURTHER-STUDIES ON PALYTOXIN .2. STRUCTURE OF PALYTOXIN
    UEMURA, D
    UEDA, K
    HIRATA, Y
    NAOKI, H
    IWASHITA, T
    [J]. TETRAHEDRON LETTERS, 1981, 22 (29) : 2781 - 2784
  • [43] Synthesis of N-aryl hydrazides by copper-catalyzed coupling of hydrazides with aryl iodides
    Wolter, M
    Klapars, A
    Buchwald, SL
    [J]. ORGANIC LETTERS, 2001, 3 (23) : 3803 - 3805
  • [44] Ambient temperature, Ullmann-like reductive coupling of aryl, heteroaryl, and alkenyl halides
    Zhang, SJ
    Zhang, DW
    Liebeskind, LS
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (08) : 2312 - 2313