Applications of mass spectrometry to signal transduction

被引:10
作者
Resing, KA
Ahn, NG
机构
[1] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80309 USA
[2] Univ Colorado, Howard Hughes Med Inst, Boulder, CO 80309 USA
关键词
D O I
10.1016/S0079-6107(98)00048-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Advances in mass spectrometry instrumentation, protocols for sample handling, and computational methods provide powerful new approaches to solving problems in analytical biochemistry. This review summarizes recent work illustrating ways in which mass spectrometry has been used to address questions relevant to signal transduction. Rather than encompass all of the instruments or methodologies that might be brought to bear on these problems, we present an overview of commonly used techniques, promising new methodologies, and some applications. (C) 1999 Elsevier Science Ltd. All rights reserved.
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页码:501 / 523
页数:23
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