Stem cells in the umbilical cord

被引：298

作者：

Weiss, Mark L. ^{[1
]}

Troyer, Deryl L.

机构：

[1] Kansas State Univ, Dept Anat & Physiol, Coll Vet Med, Manhattan, KS 66506 USA

来源：

STEM CELL REVIEWS | 2006年 / 2卷 / 02期

基金：

美国国家卫生研究院;

关键词：

umbilical cord matrix cells; Wharton's Jelly; mesenchymal stem cells; umbilical cord blood cells;

D O I：

10.1007/s12015-006-0022-y

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Stem cells are the next frontier in medicine. Stem cells are thought to have great therapeutic and biotechnological potential. This will not only to replace damaged or dysfunctional cells, but also rescue them and/or deliver therapeutic proteins after they have been engineered to do so. Currently, ethical and scientific issues surround both embryonic and fetal stem cells and hinder their widespread implementation. In contrast, stem cells recovered postnatally from the umbilical cord, including the umbilical cord blood cells, amnion/placenta, umbilical cord vein, or umbilical cord matrix cells, are a readily available and inexpensive source of cells that are capable of forming many different cell types (i.e., they are "multipotent"). This review will focus on the umbilical cord-derived stem cells and compare those cells with adult bone marrow-derived mesenchymal stem cells.

引用

页码：155 / 162

页数：8

共 78 条

[71] Adult stem cells: assessing the case for pluripotency [J].

Verfaillie, CM .

TRENDS IN CELL BIOLOGY, 2002, 12 (11) :502-508

[72] Mesenchymal stem cells in the Wharton's jelly of the human umbilical cord [J].

Wang, HS ;

Hung, SC ;

Peng, ST ;

Huang, CC ;

Wei, HM ;

Guo, YJ ;

Fu, YS ;

Lai, MC ;

Chen, CC .

STEM CELLS, 2004, 22 (07) :1330-1337

[73] Human umbilical cord matrix stem cells: Preliminary characterization and effect of transplantation in a rodent model of Parkinson's disease [J].

Weiss, Mark L. ;

Medicetty, Satish ;

Bledsoe, Amber R. ;

Rachakatla, Raja Shekar ;

Choi, Michael ;

Merchav, Shosh ;

Luo, Yongquan ;

Rao, Mahendra S. ;

Velagaleti, Gopalrao ;

Troyer, Deryl .

STEM CELLS, 2006, 24 (03) :781-792

[74] Transplantation of porcine umbilical cord matrix cells into the rat brain [J].

Weiss, ML ;

Mitchell, KE ;

Hix, JE ;

Medicetty, S ;

El-Zarkouny, SZ ;

Grieger, D ;

Troyer, DL .

EXPERIMENTAL NEUROLOGY, 2003, 182 (02) :288-299

[75] A niche maintaining germ line stem cells in the Drosophila ovary [J].

Xie, T ;

Spradling, AC .

SCIENCE, 2000, 290 (5490) :328-330

[76] Clonogenic analysis reveals reserve stem cells in postnatal mammals: I. Pluripotent mesenchymal stem cells [J].

Young, HE ;

Duplaa, C ;

Young, TM ;

Floyd, JA ;

Reeves, ML ;

Davis, KH ;

Mancini, GJ ;

Eaton, ME ;

Hill, JD ;

Thomas, K ;

Austin, T ;

Edwards, C ;

Cuzzourt, J ;

Parikh, A ;

Groom, J ;

Hudson, J ;

Black, AC .

ANATOMICAL RECORD, 2001, 263 (04) :350-360

[77] Human pluripotent and progenitor cells display cell surface cluster differentiation markers CD10, CD13, CD56, and MHC Class-I [J].

Young, HE ;

Steele, TA ;

Bray, RA ;

Detmer, K ;

Blake, LW ;

Lucas, PW ;

Black, AC .

PROCEEDINGS OF THE SOCIETY FOR EXPERIMENTAL BIOLOGY AND MEDICINE, 1999, 221 (01) :63-71

[78] Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats [J].

Zhao, LR ;

Duan, WM ;

Reyes, M ;

Keene, CD ;

Verfaillie, CM ;

Low, WC .

EXPERIMENTAL NEUROLOGY, 2002, 174 (01) :11-20

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