Molecular mechanisms of action of bisphosphonates

[51] BISPHOSPHONATE ACTION - ALENDRONATE LOCALIZATION IN RAT BONE AND EFFECTS ON OSTEOCLAST ULTRASTRUCTURE [J]. JOURNAL OF CLINICAL INVESTIGATION, 1991, 88 (06) : 2095 - 2105

[52] Interleukin-6 and tumor necrosis factor alpha levels after bisphosphonates treatment in vitro and in patients with malignancy [J]. BONE, 1996, 18 (02) : 133 - 139

[53] EFFECT OF ETHANE-1-HYDROXY-1,1-DIPHOSPHONATE (EHDP) AND DICHLOROMETHYLENE DIPHOSPHONATE (CL2MDP) ON CALCIFICATION AND RESORPTION OF CARTILAGE AND BONE IN TIBIAL EPIPHYSIS AND METAPHYSIS OF RATS [J]. CALCIFIED TISSUE RESEARCH, 1973, 11 (03): : 196 - 214

[54] QUANTITATIVE MORPHOMETRIC EVALUATION OF THE INHIBITORY ACTIVITY OF NEW AMINOBISPHOSPHONATES ON BONE-RESORPTION IN THE RAT [J]. CALCIFIED TISSUE INTERNATIONAL, 1986, 38 (06) : 342 - 349

[55] Protein-tyrosine phosphatase activity regulates osteoclast formation and function: Inhibition by alendronate [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (07) : 3068 - 3073

[56] SCHWEITZER DH, 1995, J BONE MINER RES, V10, P956

[57] Selander KS, 1996, MOL PHARMACOL, V50, P1127

[58] STRUCTURE-ACTIVITY-RELATIONSHIPS OF VARIOUS BISPHOSPHONATES [J]. CALCIFIED TISSUE INTERNATIONAL, 1983, 35 (01) : 87 - 99

[59] Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1997, 98 (03) : 665 - 672

[60] SIETSEMA WK, 1989, DRUG EXP CLIN RES, V15, P389

[51] BISPHOSPHONATE ACTION - ALENDRONATE LOCALIZATION IN RAT BONE AND EFFECTS ON OSTEOCLAST ULTRASTRUCTURE [J]. JOURNAL OF CLINICAL INVESTIGATION, 1991, 88 (06) : 2095 - 2105

[52] Interleukin-6 and tumor necrosis factor alpha levels after bisphosphonates treatment in vitro and in patients with malignancy [J]. BONE, 1996, 18 (02) : 133 - 139

[53] EFFECT OF ETHANE-1-HYDROXY-1,1-DIPHOSPHONATE (EHDP) AND DICHLOROMETHYLENE DIPHOSPHONATE (CL2MDP) ON CALCIFICATION AND RESORPTION OF CARTILAGE AND BONE IN TIBIAL EPIPHYSIS AND METAPHYSIS OF RATS [J]. CALCIFIED TISSUE RESEARCH, 1973, 11 (03): : 196 - 214

[54] QUANTITATIVE MORPHOMETRIC EVALUATION OF THE INHIBITORY ACTIVITY OF NEW AMINOBISPHOSPHONATES ON BONE-RESORPTION IN THE RAT [J]. CALCIFIED TISSUE INTERNATIONAL, 1986, 38 (06) : 342 - 349

[55] Protein-tyrosine phosphatase activity regulates osteoclast formation and function: Inhibition by alendronate [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (07) : 3068 - 3073

[56] SCHWEITZER DH, 1995, J BONE MINER RES, V10, P956

[57] Selander KS, 1996, MOL PHARMACOL, V50, P1127

[58] STRUCTURE-ACTIVITY-RELATIONSHIPS OF VARIOUS BISPHOSPHONATES [J]. CALCIFIED TISSUE INTERNATIONAL, 1983, 35 (01) : 87 - 99

[59] Bisphosphonates induce apoptosis in human myeloma cell lines: a novel anti-tumour activity [J]. BRITISH JOURNAL OF HAEMATOLOGY, 1997, 98 (03) : 665 - 672

[60] SIETSEMA WK, 1989, DRUG EXP CLIN RES, V15, P389