Guillain-Barre syndrome in Spain, 1985-1997:: Epidemiological and public health views

被引：24

作者：

Cuadrado, JI ^{[1
]}

de Pedro-Cuesta, J ^{[1
]}

Ara, JR ^{[1
]}

Cemillán, CA ^{[1
]}

Díaz, M ^{[1
]}

Duarte, J ^{[1
]}

Fernández, MD ^{[1
]}

Fernández, O ^{[1
]}

García-López, F ^{[1
]}

García-Merino, A ^{[1
]}

García-Montero, R ^{[1
]}

Martínez-Matos, JA ^{[1
]}

Palomo, F ^{[1
]}

Pardo, J ^{[1
]}

Tobías, A ^{[1
]}

机构：

[1] Carlos III Inst Hlth, Madrid, Spain

来源：

EUROPEAN NEUROLOGY | 2001年 / 46卷 / 02期

关键词：

Guillain-Barre syndrome; epidemiology; incidence; public health; surveillance;

D O I：

10.1159/000050769

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Retrospective demographic information and hospital record data were collected for 337 patients resident in Spain who had validated Guillain-Barre syndrome (GBS) diagnoses and clinical onset during the period 1985-1997 and had been admitted to 11 centres, covering a population of 3.9 million. The European age-adjusted GBS incidence per 100,000 for 1985-1997 among the population aged 20 and over was 0.85, with a breakdown of 1.14 in men and 0.58 in women. Incidence increased with age and time, with occasional rises that mimicked outbreaks and occurred at irregular 2- to 4-year intervals, mainly in winter. Spatial variation was modest. Respiratory and gastrointestinal infections respectively constituted 49.3 and 19.3% of recorded preceding events. The 97.5% intercentile limit, obtained from the 1985-1997 monthly incidences using predictions from a Poisson model, was proposed as the threshold value for pilot epidemiological surveillance of GBS in 1998-1999. Copyright (C) 2001 S. Karger AG, Basel.

引用

页码：83 / 91

页数：9

共 47 条

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