Bidentatoside I, a new triterpene saponin from Achyranthes bidentata

被引：26

作者：

Mitaine-Offer, AC

Marouf, A

Pizza, C

Khanh, TC

Chauffert, B

Lacaille-Dubois, MA

机构：

[1] Univ Bourgogne, Fac Pharm, Unite MIB, Lab Pharmacognosie, F-21079 Dijon, France

[2] Univ Oran, Fac Sci, Dept Biol, Oran, Algeria

[3] Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Salerno, Italy

[4] Univ Hanoi, Hanoi Coll Pharm, Dept Chem, Hanoi, Vietnam

[5] Univ Bourgogne, Fac Med, INSERM, U517,Unite Mort Cellulaire & Canc, F-21079 Dijon, France

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 02期

关键词：

D O I：

10.1021/np000464a

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Bidentatoside I (1) is a new triterpene saponin bearing an unusual dioxopropionic acid unit, isolated from the roots of Achyranthes bidentata. Structural elucidation was performed mainly by chemical and homo- and heteronuclear 2D NMR techniques. This compound did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.

引用

页码：243 / 245

页数：3

共 16 条

[1] DELETERIOUS EFFECT OF SERUM-PROTEINS ON THE AMPHOTERICIN B-INDUCED POTENTIATION OF CISPLATIN IN HUMAN COLON-CANCER CELLS [J].

ASSEM, M ;

BONVALOT, S ;

BELTRAMO, JL ;

GARRIDO, C ;

DIMANCHEBOITREL, MT ;

GENNE, P ;

REBIBOU, JM ;

CAILLOT, D ;

CHAUFFERT, B .

BRITISH JOURNAL OF CANCER, 1994, 70 (04) :631-635

[2]

Bishit G., 1993, Fitoterapia, V64, P85

[3]

Hostettmann K., 1995, SAPONINS

[4]

IDA Y, 1995, CHEM PHARM BULL, V43, P896

[5] ACHYRANTHOSIDE-A AND ACHYRANTHOSIDE-B, NOVEL CYTOTOXIC SAPONINS FROM ACHYRANTHES-FAURIEI ROOT [J].

IDA, Y ;

SATOH, Y ;

KATOH, M ;

KATSUMATA, M ;

NAGASAO, M ;

YAMAGUCHI, K ;

KAMEI, H ;

SHOJI, J .

TETRAHEDRON LETTERS, 1994, 35 (37) :6887-6890

[6] Two novel oleanolic acid saponins having a sialyl Lewis X mimetic structure from Achyranthes fauriei root [J].

Ida, Y ;

Satoh, Y ;

Katsumata, M ;

Nagasao, M ;

Hirai, Y ;

Kajimoto, T ;

Katada, N ;

Yasuda, M ;

Yamamoto, T .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1998, 8 (18) :2555-2558

[7]

JENUKEN AJ, 1993, BIOCHEM PHARMACOL, V45, P2079

[8]

Lacaille-Dubois MA, 2000, STUD NAT PROD CHEM, V21, P633

[9]

Mahato SB, 1998, PROG CH ORG NAT PROD, V74, P1

[10]

MAROUF A, 2000, IN PRESS PHARM BIOL

← 1 2 →