Highly chemo- and enantioselective arylative cyclization of alkyne-tethered electron-deficient olefins catalyzed by rhodium complexes with chiral dienes

被引：121

作者：

Shintani, R ^{[1
]}

Tsurusaki, A ^{[1
]}

Okamoto, K ^{[1
]}

Hayashi, T ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Sci, Dept Chem, Sakyo Ku, Kyoto 6068502, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 25期

关键词：

asymmetric catalysis; chemoselectivity; cyclization; diene ligands; rhodium;

D O I：

10.1002/anie.200500843

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A rhodium catalyst promotes the arylative cyclization of alkyne-tethered electron-deficient olefins in the presence of aryl boronic acids. High chemoselectivity was attained uniquely by the use of diene ligands, and high enantioselectivity was successfully realized by employing a C2-symmetric chiral bicyclo[2.2.2]octadiene ligand (see scheme). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3909 / 3912

页数：4

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