Cadherins and catenins in synapse development

被引:75
作者
Salinas, PC [1 ]
Price, SR [1 ]
机构
[1] UCL, Dept Anat & Dev Biol, London WC1E 6BT, England
基金
英国生物技术与生命科学研究理事会; 英国惠康基金;
关键词
D O I
10.1016/j.conb.2005.01.001
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Cadherin-catenin complexes have been well established as key regulators of cell adhesion. Recent work has elucidated a pivotal role for these molecules in synaptic assembly, remodelling and plasticity. Far from being mere adhesive scaffolds, cadherins might directly regulate cell signalling to modulate synaptic connectivity.
引用
收藏
页码:73 / 80
页数:8
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