Conjugate propargylation of α,β-unsaturated lactones:: a solution via 1,4-addition of (Z)-2-ethoxyvinyl anion

被引：13

作者：

Bennabi, S

Narkunan, K

Rousset, L

Bouchu, D

Ciufolini, MA

机构：

[1] Univ Lyon 1, UMR 5078, LSMO, F-69622 Villeurbanne, France

[2] Ecole Super Chim Phys Elect Lyon, F-69622 Villeurbanne, France

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 46期

关键词：

aldehydes; conjugate addition; cuprates; propargylation; pyridines;

D O I：

10.1016/S0040-4039(00)01506-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conjugate addition of (Z)-2-ethoxyvinyl anion to alpha,beta -unsaturated lactones is best effected via Noyori-type organocopper reagents. The resulting adducts may be advanced to beta -propargyllactones or utilized in the preparation of functionalized pyridines. (C) 2000 Elsevier Science Ltd. All rights reserved.

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收藏

页码：8873 / 8876

页数：4

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