Pharmaceutical drugs in the environment

被引:127
作者
Bila, DM [1 ]
Dezotti, M [1 ]
机构
[1] Univ Fed Rio de Janeiro, COPPE, BR-21945970 Rio De Janeiro, RJ, Brazil
来源
QUIMICA NOVA | 2003年 / 26卷 / 04期
关键词
pharmaceutical drugs; water pollution; environment fate;
D O I
10.1590/S0100-40422003000400015
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Pharmaceutical drugs have been detected in sewage treatment plants, surface waters, underground waters and potable waters. Some investigations have been conducted in several countries such as Germany, Brazil, Canada, United States, The Netherlands, England and Italy. Patients and animals excrete part of pharmaceuticals used for human and veterinary medicine after administration in domestic sewage or on the soil. Drugs residues which have not been completely removed during passage through a sewage treatment plant (STP) enter the aquatic environment. The effects of such residual drugs in terrestrial and aquatic organisms are scarcely known.
引用
收藏
页码:523 / 530
页数:8
相关论文
共 99 条
[91]   Drugs and personal care products as ubiquitous pollutants:: occurrence and distribution of clofibric acid, caffeine and DEET in the North Sea [J].
Weigel, S ;
Kuhlmann, J ;
Hühnerfuss, H .
SCIENCE OF THE TOTAL ENVIRONMENT, 2002, 295 (1-3) :131-141
[92]   QUANTITATION OF IBUPROFEN IN BIOLOGICAL-FLUIDS BY GAS CHROMATOGRAPHY-MASS SPECTROMETRY [J].
WHITLAM, JB ;
VINE, JH .
JOURNAL OF CHROMATOGRAPHY, 1980, 181 (3-4) :463-468
[93]   Selective degradation of ibuprofen and clofibric acid in two model river biofilm systems [J].
Winkler, M ;
Lawrence, JR ;
Neu, TR .
WATER RESEARCH, 2001, 35 (13) :3197-3205
[94]   Ecological impact of antibiotic use in animals on different complex microflora: environment [J].
Witte, W .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2000, 14 (04) :321-325
[95]   Acute and chronic toxicity of veterinary antibiotics to Daphnia magna [J].
Wollenberger, L ;
Halling-Sorensen, B ;
Kusk, KO .
CHEMOSPHERE, 2000, 40 (07) :723-730
[96]   The environmental impact of marine fish culture: Towards a sustainable future [J].
Wu, RSS .
MARINE POLLUTION BULLETIN, 1995, 31 (4-12) :159-166
[97]   Analysis of estrogens in river water and effluents using solid-phase extraction and gas chromatography-negative chemical ionisation mass spectrometry of the pentafluorobenzoyl derivatives [J].
Xiao, XY ;
McCalley, DV ;
McEvoy, J .
JOURNAL OF CHROMATOGRAPHY A, 2001, 923 (1-2) :195-204
[98]  
Zacharewski T, 1997, ENVIRON SCI TECHNOL, V31, P613
[99]   Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow (Pimephales promelas) [J].
Zerulla, M ;
Länge, R ;
Steger-Hartmann, T ;
Panter, G ;
Hutchinson, T ;
Dietrich, DR .
TOXICOLOGY LETTERS, 2002, 131 (1-2) :51-63