Fluorescence turn-on detection of hypochlorous acid via HOCl-promoted dihydrofluorescein-ether oxidation and its application in vivo

被引：120

作者：

Zhou, Yi ^{[1
,2
]}

Li, Ju-Ying ^{[1
,2
]}

Chu, Kai-Hui ^{[1
,2
]}

Liu, Ke ^{[1
,2
]}

Yao, Cheng ^{[1
,2
]}

Li, Jing-Yun ^{[3
]}

机构：

[1] Nanjing Univ Technol, State Key Lab Mat Oriented Chem Engn, Nanjing 210009, Peoples R China

[2] Nanjing Univ Technol, Coll Sci, Nanjing 210009, Peoples R China

[3] Nanjing Univ, Anim Model Res Ctr, Nanjing 210061, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 39期

关键词：

PROBE; MYELOPEROXIDASE;

D O I：

10.1039/c2cc30265a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report three new water-soluble dihydrofluorescein-ether probes FCN1, FCN2 and FCN3 for the detection of hypochlorous acid (HOCl), which were designed on the basis of a specific HOCl-promoted oxidation reaction. This work also provided a useful method to monitor the accumulated HOCl in specific organelles using a zebrafish model.

引用

页码：4677 / 4679

页数：3

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