Duodenum-preserving subtotal and total pancreatic head resections for inflammatory and cystic neoplastic lesions of the pancreas

被引:29
作者
Beger, H. G. [1 ,2 ,3 ]
Rau, B. M. [4 ]
Gansauge, F. [3 ]
Poch, B. [3 ]
机构
[1] Univ Hosp, D-89075 Ulm, Germany
[2] Univ Ulm, Dept Gen & Visceral Surg, Ulm, Germany
[3] Donauklinikum Neu Ulm, Dept Visceral Surg, D-89231 Neu Ulm, Germany
[4] Univ Rostock, Dept Gen Thorac Vasc & Transplantat Surg, D-18057 Rostock, Germany
关键词
inflammatory head mass; cystic neoplastic lesion; duodenum-preserving head resection;
D O I
10.1007/s11605-008-0472-4
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Introduction For treatment of inflammatory and benign neoplastic lesions of the pancreatic head, a subtotal or total pancreatic head resection is a limited surgical procedure with the impact of replacing the application of a Whipple procedure. The objective of this work is to describe the technical modifications of subtotal and total pancreatic head resection for inflammatory and neoplastic lesions of the pancreas. The advantages of this limited surgical procedure are the preservation of the stomach, the duodenum and the extrahepatic biliary ducts for treatment of benign lesions of the pancreatic head, papilla, and intrapancreatic segment of the common bile duct. For chronic pancreatitis with an inflammatory mass complicated by compression of the common bile duct or causing multiple pancreatic main duct stenoses and dilatations, a subtotal pancreatic head resection results in a long-lasting pain control. Performing, in addition, a biliary anastomosis or a Partington Rochelle type of pancreatic main duct drainage, respectively, is a logic and simple extension of the procedure. The rationale for the application of duodenum-preserving total pancreatic head resection for cystic neoplastic lesions are complete exstirpation of the tumor and, as a consequence, interruption of carcinogenesis of the neoplasia preventing development of pancreatic cancer. Duodenum-preserving total head resection necessitates additional biliary and duodenal anastomoses. For mono-centric IPMN, MCN, and SCA tumors, located in the pancreatic head, total duodenum-preserving pancreatic head resection can be performed without hospital mortality and resurgery for recurrency. Based on controlled clinical trials, duodenum-preserving pancreatic head resection is superior to the Whipple-type resection with regard to lower postoperative morbidity, almost no delay of gastric emptying, preservation of the endocrine function, lower frequency of rehospitalization, early professional rehabilitation, and establishment of a predisease level of quality of life. Conclusion The limited surgical procedures of subtotal or total pancreatic head resection are simple, safe, ensures free tumour margins and replace in the authors institution the application of a Whipple-type head resection.
引用
收藏
页码:1127 / 1132
页数:6
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