The role of sleep in learning and memory

被引:720
作者
Maquet, P [1 ]
机构
[1] UCL, Wellcome Dept Cognit Neurol, London WC1N 3BG, England
[2] Univ Liege, Cyclotron Res Ctr, B-4000 Liege, Belgium
关键词
D O I
10.1126/science.1062856
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Sleep has been implicated in the plastic cerebral changes that underlie learning and memory. Indications that sleep participates in the consolidation of fresh memory traces come from a wide range of experimental observations. At the network level, reactivations during steep of neuronal assemblies recently challenged by new environmental circumstances have been reported in different experimental designs. These neuronal assemblies are proposed to be involved in the processing of memory traces during steep. However, despite this rapidly growing body of experimental data, evidence for the influence of steep discharge patterns on memory traces remains fragmentary. The underlying role of steep in learning and memory has yet to be precisely characterized.
引用
收藏
页码:1048 / 1052
页数:5
相关论文
共 76 条
[71]   Memory trace reactivation in hippocampal and neocortical neuronal ensembles [J].
Sutherland, GR ;
McNaughton, B .
CURRENT OPINION IN NEUROBIOLOGY, 2000, 10 (02) :180-186
[72]   Origin of slow cortical oscillations in deafferented cortical slabs [J].
Timofeev, I ;
Grenier, F ;
Bazhenov, M ;
Sejnowski, TJ ;
Steriade, M .
CEREBRAL CORTEX, 2000, 10 (12) :1185-1199
[73]  
VERSCHOOR G, 1984, AFR J PSYCHOL, V14, P69
[74]   The case against memory consolidation in REM sleep [J].
Vertes, RP ;
Eastman, KE .
BEHAVIORAL AND BRAIN SCIENCES, 2000, 23 (06) :867-+
[75]   REACTIVATION OF HIPPOCAMPAL ENSEMBLE MEMORIES DURING SLEEP [J].
WILSON, MA ;
MCNAUGHTON, BL .
SCIENCE, 1994, 265 (5172) :676-679
[76]  
YAROUSH R, 1971, J EXP PSYCHOL, V88, P361, DOI 10.1037/h0030914