The cellular localization of vasoactive intestinal peptide (VIP) in the mouse median eminence by immuno-electron microscopy

被引：3

作者：

Dalcik, H

Chen, IL

Dalcik, C

Phelps, CJ

机构：

[1] GULHANE MIL MED ACAD,DEPT HISTOL & EMBRYOL,ETLIK 06018,ANKARA,TURKEY

[2] TULANE UNIV,SCH MED,DEPT ANAT,NEW ORLEANS,LA 70112

[3] BASKENT UNIV,BAHCELIEVLER,ANKARA,TURKEY

来源：

ACTA HISTOCHEMICA | 1996年 / 98卷 / 01期

关键词：

vasoactive intestinal peptide; median eminence; pre-embedding immunostaining; electron microscopy;

D O I：

10.1016/S0065-1281(96)80050-X

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The aim of this study was to examine, by use of pre-embedding immunocytochemistry, the ultrastructural localization of vasoactive intestinal peptide (VIP) immunoreactivity in the mouse median eminence. VIP immunoreactivity was observed in axonal profiles. The VIP-immunoreactive axonal profiles were in close proximity to non-immunoreactive axonal profiles that contained dense granular vesicles and clear vesicles and also to processes of tanycytes. VIP-immunoreactive terminals were observed in the proximity of the perivascular space and in the neuropil. Our results suggest that VIP-immunoreactive axon terminals may possibly interact with other non-immunoreactive axon terminals containing peptide and/or other transmitters at the level of the median eminence or may be released to the portal vasculature thereby to effect anterior pituitary cells.

引用

页码：53 / 59

页数：7

共 32 条

[1] VASOACTIVE INTESTINAL PEPTIDE IS A PHYSIOLOGICAL MEDIATOR OF PROLACTIN-RELEASE IN THE RAT [J].