Cerebral blood flow changes induced by subthalamic stimulation in Parkinson's disease

被引：49

作者：

Strafella, AP ^{[1
]}

Dagher, A ^{[1
]}

Sadikot, AF ^{[1
]}

机构：

[1] McGill Univ, Montreal Neurol Inst, Montreal, PQ H3A 2B4, Canada

来源：

NEUROLOGY | 2003年 / 60卷 / 06期

关键词：

D O I：

10.1212/01.WNL.0000052691.48076.92

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors used PET to show that the abnormal pattern of cerebral blood flow (CBF) activation described in PD is normalized by electrical stimulation of subthalamic nucleus. Improvement in bradykinesia correlated with increase in CBF due to stimulation in the supplementary motor area and anterior cingulate cortex. Compared to unilateral stimulation, bilateral stimulation induced a greater extent of activation in bilateral cortical areas and additional bilateral activation of globus pallidus.

引用

页码：1039 / 1042

页数：4

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