Polymer vesicles containing small vesicles within interior aqueous compartments and pH-Responsive transmembrane channels

被引：164

作者：

Chiu, Hsin-Cheng ^{[1
]}

Lin, Yue-Wen ^{[1
]}

Huang, Yi-Fong ^{[1
]}

Chuang, Chih-Kai ^{[1
]}

Chern, Chorng-Shyan ^{[2
]}

机构：

[1] Natl Chung Hsing Univ, Dept Chem Engn, Taichung 402, Taiwan

[2] Natl Taiwan Univ Sci & Technol, Dept Chem Engn, Taipei 106, Taiwan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2008年 / 47卷 / 10期

关键词：

biomimetic systems; multivesicles; self-assembly; transmembrane channels; vesicles;

D O I：

10.1002/anie.200704078

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Multivesicle assemblies with pH-responsive transmembrane channels in the vesicle walls (see picture) were made by two-step double emulsion of copolymers comprising acrylic acid and acrylate of 1,2-distearoyl-rac-glycerol. These assemblies mimic eukaryotic cells, which contain functional organelles within the cell walls. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

收藏

页码：1875 / 1878

页数：4

相关论文

共 35 条

[1] Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-triggered controlled release vesicles [J].

Ahmed, F ;

Discher, DE .

JOURNAL OF CONTROLLED RELEASE, 2004, 96 (01) :37-53

[2] Vesicles and liposomes:: A self-assembly principle beyond lipids [J].

Antonietti, M ;

Förster, S .

ADVANCED MATERIALS, 2003, 15 (16) :1323-1333

[3] Polymersome encapsulated hemoglobin: A novel type of oxygen carrier [J].

Arifin, DR ;

Palmer, AF .

BIOMACROMOLECULES, 2005, 6 (04) :2172-2181

[4] Pathways of polymeric vesicle formation [J].

Battaglia, Giuseppe ;

Ryan, Anthony J. .

JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (21) :10272-10279

[5] Stimuli-responsive polypeptide vesicles by conformation-specific assembly [J].

Bellomo, EG ;

Wyrsta, MD ;

Pakstis, L ;

Pochan, DJ ;

Deming, TJ .

NATURE MATERIALS, 2004, 3 (04) :244-248

[6] Toward intelligent nanosize bioreactors: A pH-switchable, channel-equipped, functional polymer nanocontainer [J].

Broz, Pavel ;

Driamov, Sergey ;

Ziegler, Joerg ;

Ben-Haim, Nadav ;

Marsch, Stephan ;

Meier, Wolfgang ;

Hunziker, Patrick .

NANO LETTERS, 2006, 6 (10) :2349-2353

[7] WATER-SOLUBLE COPOLYMERS .49. EFFECT OF THE DISTRIBUTION OF THE HYDROPHOBIC CATIONIC MONOMER - DIMETHYLDODECYL(2-ACRYLAMIDOETHYL)AMMONIUM BROMIDE ON THE SOLUTION BEHAVIOR OF ASSOCIATING ACRYLAMIDE COPOLYMERS [J].

CHANG, YH ;

MCCORMICK, CL .

MACROMOLECULES, 1993, 26 (22) :6121-6126

[8] Artificial organelle: ATP synthesis from cellular mimetic polymersomes [J].

Choi, HJ ;

Montemagno, CD .

NANO LETTERS, 2005, 5 (12) :2538-2542

[9] Polymer vesicles [J].

Discher, DE ;

Eisenberg, A .

SCIENCE, 2002, 297 (5583) :967-973

[10]

Donath E, 1998, ANGEW CHEM INT EDIT, V37, P2202, DOI 10.1002/(SICI)1521-3773(19980904)37:16<2201::AID-ANIE2201>3.0.CO

← 1 2 3 4 →