Atorvastatin and Aβ(1-40): Not as Simple as Cholesterol Reduction in Brain and Relevance to Alzheimer Disease

被引：10

作者：

Butterfield, D. Allan ^{[1
,2
]}

机构：

[1] Univ Kentucky, Ctr Membrane Sci, Dept Chem, Lexington, KY 40506 USA

[2] Univ Kentucky, Sanders Brown Ctr Aging, Lexington, KY 40506 USA

来源：

EXPERIMENTAL NEUROLOGY | 2011年 / 228卷 / 01期

关键词：

HMG-COA REDUCTASE; NITRIC-OXIDE SYNTHASE; CELLULAR STRESS-RESPONSE; TRANSGENIC MOUSE MODEL; CENTRAL-NERVOUS-SYSTEM; A-BETA ACCUMULATION; OXIDATIVE STRESS; AMYLOID-BETA; STATIN THERAPY; LIPID-PEROXIDATION;

D O I：

10.1016/j.expneurol.2010.12.014

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

引用

页码：15 / 18

页数：4

共 86 条

[1] LOVASTATIN AND SIMVASTATIN - INHIBITORS OF HMG COA REDUCTASE AND CHOLESTEROL-BIOSYNTHESIS [J].

ALBERTS, AW .

CARDIOLOGY, 1990, 77 :14-21

[2]

Bliznakov EG, 1998, ADV THER, V15, P218

[3] Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid β-peptide (1-42) into rat brain:: Implications for Alzheimer's disease [J].

Boyd-Kimball, D ;

Sultana, R ;

Poon, HF ;

Lynn, BC ;

Casamenti, F ;

Pepeu, G ;

Klein, JB ;

Butterfield, DA .

NEUROSCIENCE, 2005, 132 (02) :313-324

[4] Involvements of the lipid peroxidation product, HNE, in the pathogenesis and progression of Alzheimer's disease [J].

Butterfield, D. Allan ;

Lange, Miranda L. Bader ;

Sultana, Rukhsana .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2010, 1801 (08) :924-929

[5] In vivo oxidative stress in brain of Alzheimer disease transgenic mice: Requirement for methionine 35 in amyloid β-peptide of APP [J].

Butterfield, D. Allan ;

Galvan, Veronica ;

Lange, Miranda Bader ;

Tang, Huidong ;

Sowell, Rena A. ;

Spilman, Patricia ;

Fombonne, Joanna ;

Gorostiza, Olivia ;

Zhang, Junli ;

Sultana, Rukhsana ;

Bredesen, Dale E. .

FREE RADICAL BIOLOGY AND MEDICINE, 2010, 48 (01) :136-144

[6] Evidence of oxidative damage in Alzheimer's disease brain:: central role for amyloid β-peptide [J].

Butterfield, DA ;

Drake, J ;

Pocernich, C ;

Castegna, A .

TRENDS IN MOLECULAR MEDICINE, 2001, 7 (12) :548-554

[7] Lipid peroxidation and protein oxidation in Alzheimer's disease brain:: Potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress [J].

Butterfield, DA ;

Lauderback, CM .

FREE RADICAL BIOLOGY AND MEDICINE, 2002, 32 (11) :1050-1060

[8] Nitric oxide in the central nervous system: neuroprotection versus neurotoxicity [J].

Calabrese, Vittorio ;

Mancuso, Cesare ;

Calvani, Menotti ;

Rizzarelli, Enrico ;

Butterfield, D. Allan ;

Stella, Anna Maria Giuffrida .

NATURE REVIEWS NEUROSCIENCE, 2007, 8 (10) :766-775

[9] Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimer's disease [J].

Calabrese, Vittorio ;

Sultana, Rukhsana ;

Scapagnini, Giovanni ;

Guagliano, Eleonora ;

Sapienza, Maria ;

Bella, Rita ;

Kanski, Jaroslaw ;

Pennisi, Giovanni ;

Mancuso, Cesare ;

Stella, Anna Maria Giuffrida ;

Butterfield, D. A. .

ANTIOXIDANTS & REDOX SIGNALING, 2006, 8 (11-12) :1975-1986

[10] Intensive versus moderate lipid lowering with statins after acute coronary syndromes [J].

Cannon, CP ;

Braunwald, E ;

McCabe, CH ;

Rader, DJ ;

Rouleau, JL ;

Belder, R ;

Joyal, SV ;

Hill, KA ;

Pfeffer, MA ;

Skene, AM .

NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (15) :1495-1504

← 1 2 3 4 5 6 7 8 9 →