Why myc? An unexpected ingredient in the stem cell cocktail

被引:102
作者
Knoepfler, Paul S. [1 ,2 ,3 ]
机构
[1] Univ Calif Davis, Sch Med, Inst Pediat Regenerat Med, Sacramento, CA 95817 USA
[2] Univ Calif Davis, Sch Med, Dept Cell Biol & Human Anat, Sacramento, CA 95817 USA
[3] Shriners Hosp Children, Sacramento, CA 95817 USA
关键词
D O I
10.1016/j.stem.2007.12.004
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Screening cocktails of candidate genes for induction of pluripotency and self-renewal in nonstem cells has identified a surprising new embryonic stem cell regulator, the myc proto-oncogene. Here the possible mechanisms by which myc controls self-renewal and pluripotency are discussed.
引用
收藏
页码:18 / 21
页数:4
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