Total synthesis of (+)-(S)-angustureine and the determination of the absolute configuration of the natural product angustureine

被引：67

作者：

Theeraladanon, C ^{[1
]}

Arisawa, M ^{[1
]}

Nakagawa, M ^{[1
]}

Nishida, A ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

来源：

TETRAHEDRON-ASYMMETRY | 2005年 / 16卷 / 04期

关键词：

D O I：

10.1016/j.tetasy.2004.12.022

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Angustureine, isolated from the bark of Galipea officinalis Hancock, is a novel quinoline alkaloid with a n-pentyl side chain at the 2-position. The total synthesis of (+)-(S)-angustureine and a determination of the absolute configuration of the natural product angustureine were achieved using ring-closing metathesis (RCM) and the Mitsunobu reaction as key steps. (C) 2005 Elsevier Ltd. All rights reserved.

引用

页码：827 / 831

页数：5

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