Unusual rate enhancement of bimolecular dehydrocondensation to form amides at the interface of micelles of fatty acid salts

被引：30

作者：

Kunishima, M ^{[1
]}

Imada, H

Kikuchi, K

Hioki, K

Nishida, J

Tani, S

机构：

[1] Kobe Gakuin Univ, Fac Pharmaceut Sci, Nishi Ku, Kobe, Hyogo 6512180, Japan

[2] PRESTO, JST, Kobe, Hyogo 6512180, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 44期

关键词：

amides; condensation; kinetics; micelles; triazines;

D O I：

10.1002/anie.200502594

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) Speeding up: A micelle-water interface acts as a suitable reaction field for dehydrocondensation. The coupling reaction of fatty acid salts with a triazine-type amphiphilic dehydrocondensing agent in a micellar system (see picture) underwent up to 2000-fold acceleration. The rate enhancement can be attributed to the higher local concentration and preorientation of the reactants in the micelles. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7254 / 7257

页数：4

共 14 条

[11] DEMONSTRATION OF EXCLUSIVE ALPHA-PEPTIDATION AT THE MICELLAR INTERFACE [J].