Proton magnetic resonance spectroscopy of the temporal lobes in schizophrenics and normal controls

被引：63

作者：

YurgelunTodd, DA

Renshaw, PF

Gruber, SA

Ed, M

Waternaux, C

Cohen, BM

机构：

[1] MCLEAN HOSP,MAILMAN RES CTR,BELMONT,MA 02178

[2] HARVARD UNIV,SCH MED,DEPT PSYCHIAT,BOSTON,MA 02115

来源：

SCHIZOPHRENIA RESEARCH | 1996年 / 19卷 / 01期

关键词：

proton magnetic resonance spectroscopy; temporal lobe; (schizophrenia);

D O I：

10.1016/0920-9964(95)00071-2

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Previous research has found structural and functional abnormalities in the temporal lobes of schizophrenic patients, often with greater impairment on the left side. This study applied proton MRS to both right and left temporal lobes of schizophrenic patients and normal control subjects. Reductions in the NAA/Cr ratio were found bilaterally for schizophrenic patients as compared to normal controls, and may be associated with reduced neuronal integrity. These results strengthen the evidence for biochemical abnormalities in the temporal lobes in schizophrenia.

引用

页码：55 / 59

页数：5

共 26 条

[21] ABNORMALITIES OF THE LEFT TEMPORAL-LOBE AND THOUGHT-DISORDER IN SCHIZOPHRENIA - A QUANTITATIVE MAGNETIC-RESONANCE-IMAGING STUDY [J].