Synthesis of pyridazines functionalized with amino acid side chains

被引：10

作者：

Mann, Enrique ^{[1
]}

Moisan, Lionel ^{[1
]}

Hou, Jun-Li ^{[1
]}

Rebek, Julius, Jr. ^{[1
]}

机构：

[1] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

TETRAHEDRON LETTERS | 2008年 / 49卷 / 05期

关键词：

pyridazine; tetrazine; Tebbe reagent; inverse electron demand Diels-Alder reaction;

D O I：

10.1016/j.tetlet.2007.11.149

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple route for the preparation of 3,4,6-substituted pyridazines is described by using Tebbe olefination of esters then Diels-Alder reaction of the resulting enol ethers with tetrazine. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：903 / 905

页数：3

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