The effectiveness of topical diclofenac in relieving discomfort following traumatic corneal abrasions

被引:18
作者
Jayamanne, DGR
Fitt, AWD
Dayan, M
Andrews, RM
Mitchell, KW
Griffiths, PG
机构
[1] NEWCASTLE GEN HOSP, DEPT OPHTHALMOL, NEWCASTLE UPON TYNE NE4 6BE, TYNE & WEAR, ENGLAND
[2] ROYAL VICTORIA INFIRM, DEPT REG MED PHYS, NEWCASTLE UPON TYNE NE1 4LP, TYNE & WEAR, ENGLAND
关键词
corneal abrasions; diclofenac; non-steroidal anti-inflammatory drugs (NSAIDs);
D O I
10.1038/eye.1997.15
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Diclofenac is a non-steroidal anti-inflammatory drug available in an ophthalmic preparation. We present a prospective randomised double-masked placebo-controlled trial involving 40 patients that assessed the effectiveness of topical diclofenac in relieving pain from traumatic corneal abrasions. Statistical analysis of visual analogue and categorical pain scores revealed a significant reduction in pain experienced by subjects in the diclofenac group (p<0.02).
引用
收藏
页码:79 / 83
页数:5
相关论文
共 15 条
[11]   PHARMACOLOGY OF DICLOFENAC SODIUM [J].
SCHOLER, DW ;
KU, EC ;
BOETTCHER, I ;
SCHWEIZER, A .
AMERICAN JOURNAL OF MEDICINE, 1986, 80 (4B) :34-38
[12]  
SCOLVILLE B, 1985, J CLIN PHARMACOL, V25, P210
[13]  
SHER NA, 1993, REFRACT CORNEAL SURG, V9, P425
[14]  
Tripathi B J, 1992, Lens Eye Toxic Res, V9, P361
[15]  
Yang ZT, 1996, INVEST OPHTH VIS SCI, V37, P501