Sensitivity model for predicting photonic crystal biosensor performance

被引：84

作者：

Block, Ian D. ^{[1
]}

Ganesh, Nikhil ^{[1
]}

Lu, Meng ^{[1
]}

Cunningham, Brian T. ^{[1
]}

机构：

[1] Univ Illinois, Urbana, IL 61801 USA

来源：

IEEE SENSORS JOURNAL | 2008年 / 8卷 / 3-4期

基金：

美国国家科学基金会;

关键词：

biomedical transducers; optical resonance;

D O I：

10.1109/JSEN.2008.917127

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

We present a model for predicting photonic crystal label-free biosensor performance based primarily on the spatial distribution of electromagnetic near fields at device resonance. To achieve maximum device sensitivity, the resonant fields can be shaped by careful choice of material and geometrical parameters. The effect of each property on the resonant mode profile, and consequently on sensor performance, is illustrated. A comparison of device sensitivity calculated by both the proposed model and direct rigorous coupled wave analysis simulation supports the validity of our model.

引用

收藏

页码：274 / 280

页数：7

相关论文

共 15 条

[1]

BALANIS C, 1989, ADV ENG ELECTROMAGNE, P200

[2] Photonic crystal optical biosensor incorporating structured low-index porous dielectric [J].

Block, Ian D. ;

Chan, Leo L. ;

Cunningham, Brian T. .

SENSORS AND ACTUATORS B-CHEMICAL, 2006, 120 (01) :187-193

[3] Label-free assays on the BIND system [J].

Cunningham, BT ;

Li, P ;

Schulz, S ;

Lin, B ;

Baird, C ;

Gerstenmaier, J ;

Genick, C ;

Wang, F ;

Fine, E ;

Laing, L .

JOURNAL OF BIOMOLECULAR SCREENING, 2004, 9 (06) :481-490

[4] Near ultraviolet-wavelength photonic-crystal biosensor with enhanced surface-to-bulk sensitivity ratio [J].

Ganesh, Nikhil ;

Block, Ian D. ;

Cunningham, Brian T. .

APPLIED PHYSICS LETTERS, 2006, 89 (02)

[5] HYDROGEN ION BUFFERS FOR BIOLOGICAL RESEARCH [J].

GOOD, NE ;

WINGET, GD ;

WINTER, W ;

CONNOLLY, TN ;

IZAWA, S ;

SINGH, RMM .

BIOCHEMISTRY, 1966, 5 (02) :467-&

[6] A NEW THEORY OF WOODS ANOMALIES ON OPTICAL GRATINGS [J].

HESSEL, A ;

OLINER, AA .

APPLIED OPTICS, 1965, 4 (10) :1275-&

[7] High-resolution biosensor spectral peak shift estimation [J].

Karl, WC ;

Pien, HH .

IEEE TRANSACTIONS ON SIGNAL PROCESSING, 2005, 53 (12) :4631-4639

[8] A new method for label-free imaging of biomolecular interactions [J].

Li, PY ;

Bo, L ;

Gerstenmaier, J ;

Cunningham, BT .

SENSORS AND ACTUATORS B-CHEMICAL, 2004, 99 (01) :6-13

[9] Photonic devices enabled by waveguide-mode resonance effects in periodically modulated films [J].

Magnusson, R ;

Ding, Y ;

Lee, KJ ;

Shin, D ;

Priambodo, PS ;

Young, PP ;

Maldonado, TA .

NANO-AND MICRO-OPTICS FOR INFORMATION SYSTEMS, 2003, 5225 :20-34

[10] Evanescent wave sensor of sensitivity larger than a free space wave [J].

Parriaux, O ;

Lambeck, PV ;

Hoekstra, HJWM ;

Veldhuis, GJ ;

Pandraud, G .

OPTICAL AND QUANTUM ELECTRONICS, 2000, 32 (6-8) :909-921