Immune intervention with anti-CD3 in diabetes

被引：9

作者：

Harlan, DM ^{[1
]}

von Herrath, M

机构：

[1] NIDDK, Islet & Autoimmun Branch, NIH, Bethesda, MD 20812 USA

[2] La Jolla Inst Allergy & Immunol, Immune Regulat Lab, San Diego, CA 92121 USA

来源：

NATURE MEDICINE | 2005年 / 11卷 / 07期

关键词：

D O I：

10.1038/nm0705-716

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Autoimmune processes that destroy insulin-producing cells in the pancreas cause type 1 diabetes. To prevent the disease, autoreactive immune cells need to be suppressed or eliminated without deleterious side effects. Results from a phase 2 clinical trial take steps in this direction.

引用

页码：716 / 718

页数：4

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