Nanomechanical assay to investigate the selectivity of binding interactions between volatile benzene derivatives

被引:18
作者
Raorane, Digvijay [1 ]
Lim, Si-Hyung Shawn [2 ]
Majumdar, Arun [1 ,3 ]
机构
[1] Univ Calif Berkeley, Dept Mech Engn, Berkeley, CA 94704 USA
[2] Kookmin Univ, Sch Mech & Automot Engn, Seoul, South Korea
[3] Univ Calif Berkeley, Lawrence Berkeley Lab, Div Mat Sci, Berkeley, CA 94720 USA
基金
美国国家科学基金会;
关键词
D O I
10.1021/nl080829s
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Understanding the interactions between aromatic gas molecules and various simple aromatic receptor molecules is important in developing selective receptors for volatile organic compounds (VOCs). Here, five benzene thiols with different functional end groups were used to investigate the weak binding of aromatic vapors such as dinitrotolouene (DNT) and toluene. A multiplexed microcantilever array in conjunction with a very low concentration vapor generation system was developed to study multiple receptor-target interactions simultaneously. Differential nanomechanical responses of such devices provided insight into the influence of various chemical and structural features of such molecules.
引用
收藏
页码:2229 / 2235
页数:7
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