A new route for the synthesis of pyrrolo[2,1-c][1,4]benzodiazepine antibiotics via oxidation of cyclic secondary amine

被引：28

作者：

Kamal, A

Rao, NV

机构：

[1] Indian Inst. of Chemical Technology

来源：

CHEMICAL COMMUNICATIONS | 1996年 / 03期

关键词：

D O I：

10.1039/cc9960000385

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of the imine-containing pyrrolo[2,1-c][1,4]benzodiazepine DNA-binding antitumour antibiotics was achieved by a new method of oxidation of cyclic secondary amines which does not endanger the stereochemical integrity of the C-11a position.

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页码：385 / 386

页数：2

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