Synthesis and growth inhibitory properties of glucosamine-derived glycerolipids

被引:56
作者
Yang, GL
Franck, RW
Bittman, R
Samadder, P
Arthur, G
机构
[1] CUNY Hunter Coll, Dept Chem, New York, NY 10021 USA
[2] CUNY Queens Coll, Flushing, NY 11367 USA
[3] Univ Manitoba, Dept Biochem & Med Genet, Winnipeg, MB R3E 0W3, Canada
关键词
D O I
10.1021/ol006783a
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] 2-Amino C-glycerolipid Ib was synthesized by using the Ramberg-Backlund rearrangement as the key step. beta -C-Glycerolipid Ib exhibits in vitro antiproliferative effects strikingly similar to those of O-glycoside analogue 1a.
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页码:197 / 200
页数:4
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