Statistical analysis of six STR loci located in MHC region in Iranian population for preimplantation genetic diagnosis

被引：4

作者：

Korzebor, A.

Zamani, M.

Nouri, K.

Modarressi, M. H. ^{[1
]}

机构：

[1] Med Sci Tehran Univ, Dept Med Genet, Tehran, Iran

[2] Avesina Res Inst, Dept Genet & Biotechnol, Reprod Biotechnol Res Ctr, Tehran, Iran

[3] Med Sci Tehran Univ, Dept Epidemiol & Biostat, Tehran, Iran

来源：

INTERNATIONAL JOURNAL OF IMMUNOGENETICS | 2007年 / 34卷 / 06期

关键词：

D O I：

10.1111/j.1744-313X.2007.00719.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We studied allele frequency and other statistical parameters of six short-tandem repeat (STR) loci: D6S265, D6S439, D6S105, D6S82-1, MICA, and MOGd, which are located in major histocompatibility complex (MHC) region (6p21.3) in 101 Iranian individuals. STR polymorphisms were analysed by PCR and polyacrylamide gel electrophoresis and subsequent comparison with standard (allelic) ladders. Exact tests of Hardy-Weinberg equilibrium were performed for the six loci. All loci, except the MOGd (P = 0.4291), were in Hardy-Weinberg equilibrium. These data may be useful in PGD-HLA matching and forensic science.

引用

页码：441 / 443

页数：3