Detection of NDM-1-Producing Klebsiella pneumoniae in Kenya

被引：160

作者：

Poirel, Laurent ^{[1
]}

Revathi, Gunturu ^{[2
]}

Bernabeu, Sandrine ^{[1
]}

Nordmann, Patrice ^{[1
]}

机构：

[1] Hop Bicetre, AP HP, Fac Med Paris Sud, Serv Bacteriol Virol,INSERM,U914 Emerging Resista, K Bicetre, France

[2] Aga Khan Univ Hosp, Dept Pathol, Nairobi, Kenya

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2011年 / 55卷 / 02期

关键词：

BETA-LACTAMASE; CARBAPENEMASES; EMERGENCE;

D O I：

10.1128/AAC.01247-10

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla(NDM-1) carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including beta-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.

引用

页码：934 / 936

页数：3

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