Spread of OXA-48-Positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey

被引：197

作者：

Carrer, Amelie ^{[1
]}

Poirel, Laurent ^{[1
]}

Eraksoy, Haluk ^{[2
]}

Cagatay, A. Atahan ^{[2
]}

Badur, Selim ^{[3
]}

Nordmann, Patrice ^{[1
]}

机构：

[1] Hop Bicetre, Serv Bacteriol Virol, Fac Med Paris Sud, INSERM U Emerging Resistance Antibiot 914,AP HP, F-94275 Le Kremlin Bicetre, France

[2] Istanbul Fac Med, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey

[3] Istanbul Fac Med, Dept Microbiol, Istanbul, Turkey

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 08期

关键词：

D O I：

10.1128/AAC.01672-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The first outbreak of carbapenem-resistant Klebsiella pneumoniae isolates producing the plasmid-encoded carbapenem-hydrolyzing oxacillinase OXA-48 is reported. The 39 isolates belonged to two different clones and were collected at the University Hospital of Istanbul, Turkey, from May 2006 to February 2007, and they coproduced various beta-lactamases (SHV-12, OXA-9, and TEM-1 for clone A and CTX-M-15, TEM-1, and OXA-1 for clone B).

引用

页码：2950 / 2954

页数：5

共 26 条

[1] Carbapenem-hydrolyzing oxacillinase, OXA-48, persists in Klebsiella pneumoniae in Istanbul, Turkey [J].

Aktas, Zerrin ;

Kayacan, Cigdem Bal ;

Schneider, Ines ;

Can, Baris ;

Midilli, Kenan ;

Bauernfeind, Adolf .

CHEMOTHERAPY, 2008, 54 (02) :101-106

[2] Functional characterization of IS1999, an IS4 family element involved in mobilization and expression of β-lactam resistance genes [J].

Aubert, Daniel ;

Naas, Thierry ;

Heritier, Claire ;

Poirel, Laurent ;

Nordmann, Patrice .

JOURNAL OF BACTERIOLOGY, 2006, 188 (18) :6506-6514

[3] Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the loss of an outer membrane protein [J].

Bradford, PA ;

Urban, C ;

Mariano, N ;

Projan, SJ ;

Rahal, JJ ;

Bush, K .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (03) :563-569

[4] Rapid spread of carbapenem-resistant Klebsiella pneumoniae in New York City -: A new threat to our antibiotic armamentarium [J].

Bratu, S ;

Landman, D ;

Haag, R ;

Recco, R ;

Eramo, A ;

Alam, M ;

Quale, J .

ARCHIVES OF INTERNAL MEDICINE, 2005, 165 (12) :1430-1435

[5] Bloodstream infections caused by multidrug-resistant Klebsiella pneumoniae producing the carbapenem-hydrolysing VIM-1 metallo-β-lactamase:: first Italian outbreak [J].

Cagnacci, Simone ;

Gualco, Laura ;

Roveta, Simona ;

Mannelli, Stefania ;

Borgianni, Luisa ;

Docquier, Jean-Denis ;

Dodi, Ferdinando ;

Centanaro, Monica ;

Debbia, Eugenio ;

Marchese, Anna ;

Rossolini, Gian Maria .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2008, 61 (02) :296-300

[6] Emergence of Serratia marcescens, Klebsiella pneumoniae, and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing β-lactamase KPC-2 in intensive care units of a Chinese hospital [J].

Cai, Jia Chang ;

Zhou, Hong Wei ;

Zhang, Rong ;

Chen, Gong-Xiang .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (06) :2014-2018

[7]

*CLIN LAB STAND I, 2008, M100S18 CLIN LAB S S

[8] Molecular epidemiology of the integron-located VEB-1 extended-spectrum β-lactamase in nosocomial enterobacterial isolates in Bangkok, Thailand [J].

Girlich, D ;

Poirel, L ;

Leelaporn, A ;

Karim, A ;

Tribuddharat, C ;

Fennewald, M ;

Nordmann, P .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (01) :175-182

[9] Molecular epidemiology of an outbreak due to IRT-2 β-lactamase-producing strains of Klebsiella pneumoniae in a geriatric department [J].

Girlich, D ;

Karim, A ;

Poirel, L ;

Cavin, MH ;

Verny, C ;

Nordmann, P .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2000, 45 (04) :467-473

[10] Carbapenem-resistant Escherichia coli and Klebsiella pneumoniae isolates from Turkey with OXA-48-like carbapenemases and outer membrane protein loss [J].

Guelmez, Dolunay ;

Woodford, Neil ;

Palepou, Marie-France I. ;

Mushtaq, Shazad ;

Metan, Gokhan ;

Yakupogullari, Yusuf ;

Kocagoz, Sesin ;

Uzun, Omrum ;

Hascelik, Gulsen ;

Livermore, David M. .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2008, 31 (06) :523-526

← 1 2 3 →