Molecular epidemiology of an outbreak due to IRT-2 β-lactamase-producing strains of Klebsiella pneumoniae in a geriatric department

被引：26

作者：

Girlich, D

Karim, A

Poirel, L

Cavin, MH

Verny, C

Nordmann, P

机构：

[1] Hop Bicetre, Fac Med Paris Sud, Assistance Publ Hop Paris, Serv Bacteriol Virol, F-94275 Le Kremlin Bicetre, France

[2] Hop Bicetre, Fac Med Paris Sud, Assistance Publ Hop Paris, Serv Geriatr, F-94275 Le Kremlin Bicetre, France

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2000年 / 45卷 / 04期

关键词：

D O I：

10.1093/jac/45.4.467

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

In February 1998, 195 patients in the geriatric department of a French hospital were screened for the presence of co-amoxiclav-resistant Klebsiella pneumoniae, Eleven co-amoxiclav-resistant isolates obtained all produced an identical IRT-2 beta-lactamase. These K. pneumoniae isolates were clonally related and harboured a c. 55 kb non-conjugative plasmid encoding a non-class-1 integron-located bla(IRT-2) gene. This study underlines that geriatric departments may be a reservoir for antibiotic-resistant strains and that IRT beta-lactamase-producing strains may be nosocomial pathogens.

引用

页码：467 / 473

页数：7

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