Cytotoxic constituents of the fruits of Cananga odorata

被引：77

作者：

Hsieh, TJ

Chang, FR

Chia, YC

Chen, CY

Chin, HF

Wu, YC ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Grad Inst Nat Prod, Kaohsiung 807, Taiwan

[2] Tajen Inst Technol, Dept Food Sanitat, Pingtung 907, Taiwan

[3] Fooyin Inst Technol, Dept Nursing, Kaohsiung Cty 831, Taiwan

来源：

JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 05期

关键词：

D O I：

10.1021/np0005208

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A new guaipyridine sesquiterpene alkaloid, cananodine (1), and two new eudesmane sesquiterpines, cryptomeridiol 11-alpha -L-rhamnoside (2) and gamma -eudesmol 11-alpha -L-rhamnoside (3), along with gamma -eudesmol (4), were isolated from the fruits of Cananga odorata. The structures of compounds 1-3 were established on the basis of NMR and MS methods. In addition, compounds 1-4 and four previously reported alkaloids, cleistopholine (5), N-trans-feruloyltyramine (8), (+)-ushinsunine-beta -N-oxide (7), and lyscamine (8), were evaluated for cytotoxicity against two human hepatocarcinoma cell lines.

引用

收藏

页码：616 / 619

页数：4

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