Concomitant monoreduction and hydrogenation of unsaturated cyclic imides to lactams catalyzed by ruthenium compounds

被引：41

作者：

Aoun, R ^{[1
]}

Renaud, JL ^{[1
]}

Dixneuf, PH ^{[1
]}

Bruneau, C ^{[1
]}

机构：

[1] Univ Rennes 1, CNRS, UMR 6509, Inst Chim Rennes, F-35042 Rennes, France

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 13期

基金：

美国国家卫生研究院;

关键词：

hydrogenation; lactams; reduction; ruthenium;

D O I：

10.1002/anie.200462996

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

(Chemical Equation Presented) One for two: [Ru4H 6(p-cymene)4]Cl2 and [RuCl2(p- cymene)]2, [Ru], are efficient catalyst precursors for the selective transformation of cyclic imides into saturated lactams (see scheme). The catalytic systems operate with the same reagent (H2) to perform two transformations, namely, monoreduction of the carbonyl groups and hydrogenation of C=C bonds, with the release only of water, which is the solvent of the reaction. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2021 / 2023

页数：3

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