Genetic interference in protozoa

被引：11

作者：

Bastin, P

Galvani, A

Sperling, L

机构：

[1] CNRS, Ctr Genet Mol, F-91198 Gif Sur Yvette, France

[2] Univ Manchester, Sch Biol Sci, Manchester M13 9PT, Lancs, England

来源：

RESEARCH IN MICROBIOLOGY | 2001年 / 152卷 / 02期

关键词：

gene silencing; RNA; double-stranded; Paramecium; Trypanosoma;

D O I：

10.1016/S0923-2508(01)01182-2

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

RNA interference first described in Caenorhabditis elegans and transgene-induced post-transcriptional gene silencing first described in plants and fungi now appear as different means of activating a conserved and ancient mechanism that can protect genomes against viruses and transposons and perhaps also control expression of endogenous genes. We present here similar genetic interference phenomena in highly divergent protozoa, Trypanosoma and Paramecium, and look ahead to what contribution these microorganisms could bring to this fast-moving area. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

页码：123 / 129

页数：7

共 60 条

[1] Double-stranded RNA as a template for gene silencing [J].