Treatment Outcomes of Isoniazid-Resistant Tuberculosis Patients, Western Cape Province, South Africa

被引：69

作者：

Jacobson, Karen R. ^{[1
]}

Theron, Danie ^{[2
]}

Victor, Thomas C. ^{[3
]}

Streicher, Elizabeth M. ^{[3
]}

Warren, Robin M. ^{[3
]}

Murray, Megan B. ^{[4
]}

机构：

[1] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02114 USA

[2] Brewelskloof Hosp, Worcester, MA USA

[3] Univ Stellenbosch, Dept Sci & Technol, Natl Res Fdn Ctr Excellence Biomed TB Res, Med Res Council Ctr Mol & Cellular Biol, Cape Town, South Africa

[4] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA 02115 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2011年 / 53卷 / 04期

关键词：

D O I：

10.1093/cid/cir406

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We report treatment outcomes from a retrospective cohort of patients with isoniazid-monoresistant tuberculosis in rural South Africa. Sixteen percent of patients had poor outcomes, 61% of whom progressed to multidrug-resistant tuberculosis. These data reveal the need for early identification and aggressive follow-up of isoniazid monoresistance to increase treatment success.

引用

页码：369 / 372

页数：4

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