Pathogenesis of neonatal Streptococcus agalactiae infections

被引:83
作者
Spellerberg, B
机构
[1] Univ Hosp Aachen, Inst Med Microbiol, D-52057 Aachen, Germany
[2] Univ Hosp Aachen, Natl Reference Ctr Streptococci, D-52057 Aachen, Germany
关键词
Streptococcus agalactiae; group B streptococci; pathogenesis; infectious diseases; neonatal infections;
D O I
10.1016/S1286-4579(00)01328-9
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Streptococcus algalactiae is an important human pathogen causing severe neonatal infections. During the course of infection, S. algalactiae colonizes and invades a number of different host compartments. Bacterial molecules including the polysaccharide capsule, the hemolysin, the C5a peptidase, the C-proteins, the hyaluronate lyase and a number of unknown bacterial components determine the interaction with host tissues. This review summarizes our current knowledge about these interactions. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码:1733 / 1742
页数:10
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