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The endocannabinoid system: Drug targets, lead compounds, and potential therapeutic applications

被引：289
作者：
Lambert, DM
Fowler, CJ
机构：
[1] Catholic Univ Louvain, CMFA, Unite Chim Pharmaceut & Radiopharm, B-1200 Brussels, Belgium
[2] Umea Univ, Dept Pharmacol & Clin Neurosci, SE-90187 Umea, Sweden
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 2005年 / 48卷 / 16期
关键词：
D O I：
10.1021/jm058183t
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：5059 / 5087
页数：29
相关论文
共 428 条
[41]   Binding of anandamide to bovine serum albumin [J].
Bojesen, IN ;
Hansen, HS .
JOURNAL OF LIPID RESEARCH, 2003, 44 (09) :1790-1794
[42]  
Bonhaus DW, 1998, J PHARMACOL EXP THER, V287, P884
[43]   MICROSOMAL CYTOCHROME P450-MEDIATED LIVER AND BRAIN ANANDAMIDE METABOLISM [J].
BORNHEIM, LM ;
KIM, KY ;
CHEN, BL ;
CORREIA, MA .
BIOCHEMICAL PHARMACOLOGY, 1995, 50 (05) :677-686
[44]   ACTIVATION OF MITOGEN-ACTIVATED PROTEIN-KINASES BY STIMULATION OF THE CENTRAL CANNABINOID RECEPTOR CB1 [J].
BOUABOULA, M ;
POINOTCHAZEL, C ;
BOURRIE, B ;
CANAT, X ;
CALANDRA, B ;
RINALDICARMONA, M ;
LEFUR, G ;
CASELLAS, P .
BIOCHEMICAL JOURNAL, 1995, 312 :637-641
[45]   STIMULATION OF CANNABINOID RECEPTOR CB1 INDUCES KROX-24 EXPRESSION IN HUMAN ASTROCYTOMA-CELLS [J].
BOUABOULA, M ;
BOURRIE, B ;
RINALDICARMONA, M ;
SHIRE, D ;
LEFUR, G ;
CASELLAS, P .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (23) :13973-13980
[46]   A selective inverse agonist for central cannabinoid receptor inhibits mitogen-activated protein kinase activation stimulated by insulin or insulin-like growth factor 1 - Evidence for a new model of receptor/ligand interactions [J].
Bouaboula, M ;
Perrachon, S ;
Milligan, L ;
Canat, X ;
RinaldiCarmona, M ;
Portier, M ;
Barth, F ;
Calandra, B ;
Pecceu, F ;
Lupker, J ;
Maffrand, JP ;
LeFur, G ;
Casellas, P .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (35) :22330-22339
[47]   Cannabinoid receptor CB1 activates the Na+/H+ exchanger NHE-1 isoform via Gi-mediated mitogen activated protein kinase signaling transduction pathways [J].
Bouaboula, M ;
Bianchini, L ;
McKenzie, FR ;
Pouyssegur, J ;
Casellas, P .
FEBS LETTERS, 1999, 449 (01) :61-65
[48]   Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling [J].
Bracey, MH ;
Hanson, MA ;
Masuda, KR ;
Stevens, RC ;
Cravatt, BF .
SCIENCE, 2002, 298 (5599) :1793-1796
[49]   Cloning and molecular characterization of the rat CB2 cannabinoid receptor [J].
Brown, SM ;
Wager-Miller, J ;
Mackie, K .
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 2002, 1576 (03) :255-264
[50]   Receptor-independent effects of natural cannabinoids in rat peritoneal mast cells in vitro [J].
Bueb, JL ;
Lambert, DM ;
Tschirhart, EJ .
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2001, 1538 (2-3) :252-259
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