The Role of Platelet Reactivity and Genotype Testing in the Prevention of Atherothrombotic Cardiovascular Events Remains Unproven

被引:49
作者
Krishna, Vamsi [1 ]
Diamond, George A. [1 ]
Kaul, Sanjay [1 ]
机构
[1] Cedars Sinai Med Ctr, Div Cardiol, Los Angeles, CA 90048 USA
关键词
PERCUTANEOUS CORONARY INTERVENTION; CLOPIDOGREL-TREATED PATIENTS; OF-FUNCTION POLYMORPHISM; PROTON PUMP INHIBITORS; FOUNDATION TASK-FORCE; CYP2C19; GENOTYPE; STENT THROMBOSIS; ANTIPLATELET THERAPY; CLINICAL-EFFICACY; GENETIC-VARIANTS;
D O I
10.1161/CIRCULATIONAHA.111.075242
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:1288 / 1303
页数:16
相关论文
共 75 条
[1]   ACCF/ACG/AHA 2010 Expert Consensus Document on the Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Focused Update of the ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents [J].
Abraham, Neena S. ;
Hlatky, Mark A. ;
Antman, Elliott M. ;
Bhatt, Deepak L. ;
Bjorkman, David J. ;
Clark, Craig B. ;
Furberg, Curt D. ;
Johnson, David A. ;
Kahi, Charles J. ;
Laine, Loren ;
Mahaffey, Kenneth W. ;
Quigley, Eamonn M. ;
Scheiman, James ;
Sperling, Laurence S. ;
Tomaselli, Gordon F. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2010, 56 (24) :2051-2066
[2]   Prasugrel Overcomes High On-Clopidogrel Platelet Reactivity Post-Stenting More Effectively Than High-Dose (150-mg) Clopidogrel The Importance of CYP2C19*2 Genotyping [J].
Alexopoulos, Dimitrios ;
Dimitropoulos, Gerasimos ;
Davlouros, Periklis ;
Xanthopoulou, Ioanna ;
Kassimis, George ;
Stavrou, Eleana F. ;
Hahalis, George ;
Athanassiadou, Aglaia .
JACC-CARDIOVASCULAR INTERVENTIONS, 2011, 4 (04) :403-410
[3]   Variability in individual responsiveness to clopidogrel - Clinical implications, management, and future perspectives [J].
Angiolillo, Dominick J. ;
Fernandez-Ortiz, Antonio ;
Bernardo, Esther ;
Alfonso, Fernando ;
Macaya, Carlos ;
Bass, Theodore A. ;
Costa, Marco A. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2007, 49 (14) :1505-1516
[4]   Optimizing Platelet Inhibition in Clopidogrel Poor Metabolizers Therapeutic Options and Practical Considerations [J].
Angiolillo, Dominick J. ;
Ueno, Masafumi .
JACC-CARDIOVASCULAR INTERVENTIONS, 2011, 4 (04) :411-414
[5]  
[Anonymous], FDA DRUG SAF COMM RE
[6]   Prognostic significance of high on-clopidogrel platelet reactivity after percutaneous coronary intervention: Systematic review and meta-analysis [J].
Aradi, Daniel ;
Komocsi, Andras ;
Vorobcsuk, Andras ;
Rideg, Orsolya ;
Tokes-Fuzesi, Margit ;
Magyarlaki, Tamas ;
Horvath, Ivan Gabor ;
Serebruany, Victor L. .
AMERICAN HEART JOURNAL, 2010, 160 (03) :543-551
[7]   Bleeding risk associated with 1 year of dual antiplatelet therapy after percutaneous coronary intervention: Insights from the Clopidogrel for the Reduction of Events During Observation (CREDO) trial [J].
Aronow, Herbert D. ;
Steinhubl, Steven R. ;
Brennan, Danielle M. ;
Berger, Peter B. ;
Topol, Eric J. .
AMERICAN HEART JOURNAL, 2009, 157 (02) :369-374
[8]   Impact of CYP2C19 variant genotypes on clinical efficacy of antiplatelet treatment with clopidogrel: systematic review and meta-analysis [J].
Bauer, Tim ;
Bouman, Heleen J. ;
van Werkum, Jochem W. ;
Ford, Neville F. ;
ten Berg, Jurrien M. ;
Taubert, Dirk .
BMJ-BRITISH MEDICAL JOURNAL, 2011, 343
[9]   Clopidogrel with or without Omeprazole in Coronary Artery Disease. [J].
Bhatt, Deepak L. ;
Cryer, Byron L. ;
Contant, Charles F. ;
Cohen, Marc ;
Lanas, Angel ;
Schnitzer, Thomas J. ;
Shook, Thomas L. ;
Lapuerta, Pablo ;
Goldsmith, Mark A. ;
Laine, Loren ;
Scirica, Benjamin M. ;
Murphy, Sabina A. ;
Cannon, Christopher P. .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (20) :1909-1917
[10]   Adjusted clopidogrel loading doses according to vasodilator-stimulated phosphoprotein phosphorylation index decrease rate of major adverse cardiovascular events in patients with clopidogrel resistance: A multicenter randomized prospective study [J].
Bonello, Laurent ;
Camoin-Jau, Laurence ;
Arques, Stephane ;
Boyer, Christian ;
Panagides, Dimitri ;
Wittenberg, Olivier ;
Simeoni, Marie-Claude ;
Barragan, Paul ;
Dignat-George, Francoise ;
Paganelli, Franck .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 51 (14) :1404-1411