Multiplex approaches in protein microarray technology

被引:35
作者
Kersten, B
Wanker, EE
Hoheisel, JD
Angenendt, P
机构
[1] German Canc Res Ctr, D-69120 Heidelberg, Germany
[2] Max Delbruck Ctr Mol Med, D-13125 Berlin, Germany
关键词
antibody chip; high throughput; multiplex; protein microarray;
D O I
10.1586/14789450.2.4.499
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The success of genome sequencing projects has provided the basis for systematic analysis of protein function and has led to a shift from the description of single molecules to the characterization of complex samples. Such a task would not be possible without the provision of appropriate high-throughput technologies, such as protein microarray technology. In addition, the increasing number of samples necessitates the adaptation of such technologies to a multiplex format. This review will discuss protein microarray technology in the context of multiplex analysis and highlight its current prospects and limitations.
引用
收藏
页码:499 / 510
页数:12
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