Advances in glycoprotein synthesis

被引：76

作者：

Liu, L

Bennett, CS

Wong, CH

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

CHEMICAL COMMUNICATIONS | 2006年 / 01期

关键词：

D O I：

10.1039/b513165k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The development of chemical and enzymatic methods for the synthesis of homogeneous glycoproteins is a fascinating challenge at the interface between chemistry and biology. Discussed here are the currently available methods for preparation of homogeneous glycoproteins. These methods include (1) glycopeptide ligation; (2) glycoprotein remodeling; and (3) in vivo suppressor tRNA technology.

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页码：21 / 33

页数：13

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