Polysialic acid and the regulation of cell interactions

被引：143

作者：

Rutishauser, U

机构：

[1] Department of Genetics, School of Medicine, Case Western Reserve University, Cleveland, OH 44106-4955

来源：

CURRENT OPINION IN CELL BIOLOGY | 1996年 / 8卷 / 05期

关键词：

D O I：

10.1016/S0955-0674(96)80109-8

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Polysialic acid, a unique glycosylation of the neural cell adhesion molecule, is highly regulated in its expression. Its function is manifested in the modulation of cell interactions, probably through its unusual physical properties. Recent advances have clarified the enzymatic mechanism of polysialic acid biosynthesis, expanded its role in cell migration and axon guidance, and suggested that it promotes plasticity in the adult nervous system.

引用

页码：679 / 684

页数：6

共 46 条

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