The PIR-International Protein Sequence Database

被引：62

作者：

Barker, WC ^{[1
]}

Garavelli, JS

McGarvey, PB

Marzec, CR

Orcutt, BC

Srinivasarao, GY

Yeh, LSL

Ledley, RS

Mewes, HW

Pfeiffer, F

Tsugita, A

Wu, C

机构：

[1] Natl Biomed Res Fdn, Prot Informat Resource, Washington, DC 20007 USA

[2] Max Planck Inst Biochem, Munich Informat Ctr Prot Sequences, GSF Forschungszentrum Umwelt & Gesundheit, D-82152 Martinsried, Germany

[3] Sci Univ Tokyo, Japan Int Prot Informat Database, Noda, Chiba, Japan

[4] Univ Texas, Ctr Hlth, Dept Epidemiol Biomath, Tyler, TX 75710 USA

来源：

NUCLEIC ACIDS RESEARCH | 1999年 / 27卷 / 01期

关键词：

D O I：

10.1093/nar/27.1.39

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Protein Information Resource (PIR;http://www-nbrf.georgetown.edu/pir/) supports research on molecular evolution, functional genomics, and computational biology by maintaining a comprehensive, non-redundant, well-organized and freely available protein sequence database. Since 1988 the database has been maintained collaboratively by PIR-International, an international association of data collection centers cooperating to develop this resource during a period of explosive growth in new sequence data and new computer technologies. The PIR Protein Sequence Database entries are classified into superfamilies, families and homology domains, for which sequence alignments are available. Full-scale family classification supports comparative genomics research, aids sequence annotation, assists database organization and improves database integrity. The PIR WWW server supports direct on-line sequence similarity searches, information retrieval, and knowledge discovery by providing the Protein Sequence Database and other supplementary databases. Sequence entries are extensively cross-referenced and hypertext-linked to major nucleic acid, literature, genome, structure, sequence alignment and family databases. The weekly release of the Protein Sequence Database can be accessed through the PIR Web site. The quarterly release of the database is freely available from our anonymous FTP server and is also available on CD-ROM with the accompanying ATLAS database search program.

引用

页码：39 / 43

页数：5

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